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Total 200 results found since Jan 2013.
Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.
Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease
https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/
With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models.
The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
3 Ways Consumers are Putting the Pressure on Health Plans
The following is a guest article by Mike Pattwell, Principal Business Advisor, Value Based Care at Edifecs
Consumers are at the heart of healthcare — their fears are forcing healthcare innovators to shift priorities to deliver consumer-centric digital health offerings. This is true today, tomorrow, and far into the future.
With inflation brings financial concerns that lead to cost-cutting efforts often resulting in poorer health outcomes from millions of Americans. Consumers are looking for smarter ways to save on healthcare, forcing insurance providers to make marked changes to the way they conduct outreach and how they...
Source: EMR and HIPAA - June 21, 2023 Category: Information Technology Authors: Guest Author Tags: Communication and Patient Experience Health IT Company Healthcare IT Telemedicine and Remote Monitoring APIs Application Programming Interfaces Consumers Edifecs EHR FHIR Health Plans Healthcare Consumers Healthcare Insurance Compa Source Type: blogs
Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT.
Age-Related Dysfunction of Water Homeostasis
https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/
Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cardiogenic Shock with Fulminant Myocarditis Following Covid-19 Infection Tends to Have Slightly Worse Outcome Than That From Covid-19 Vaccinations
Multiple reports of myocarditis after COVID-19 infection or COVID-19 vaccination exist, however, data is lacking on fulminant myocarditis leading to cardiogenic shock in this patient population. We conducted a literature search, on outcomes of fulminant myocarditis following COVID-19 infection or COVID-19 vaccination.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: A. Etuk, O. Ilonze, M. Guglin Tags: (566) Source Type: research
Hepatitis A seroprevalence among special populations in the Rio de Janeiro Metropolitan Area, Brazil
The objectives were to estimate hepatitis A virus seroprevalence in subjects attending to a travel medicine and immunization clinic in Rio de Janeiro, Brazil, and to develop a prediction model for hepatitis A virus seroprevalence. This retrospective research included individuals sequentially from April 2011 to June 2019 at a travel medicine and special population immunization clinic with an anti-hepatitis A virus IgG chemiluminescence result. Participants' data were verified via electronic medical records. Data were split into development and validation set taking 2018 as the date break. A cross-validated elastic generaliz...
Source: Cadernos de Saude Publica - March 22, 2023 Category: International Medicine & Public Health Authors: Flavio de Carvalho Luciana Gomes Pedro Brand ão Margaret Catoia Varela Mari Tuyama Danusa Ferreira Correa Ananza Taina da Silva Santos Alberto Dos Santos de Lemos Marcellus Dias da Costa Jos é Cerbino-Neto Pedro Emmanuel Alvarenga Americano do Brasil Source Type: research
Fight Aging! Newsletter, March 20th 2023
This study also provides the potential for de novo generation of complex organs in vivo.
T Cells May Play a Role in the Brain Inflammation Characteristic of Neurodegenerative Conditions
https://www.fightaging.org/archives/2023/03/t-cells-may-play-a-role-in-the-brain-inflammation-characteristic-of-neurodegenerative-conditions/
Alzheimer's disease, and other forms of neurodegenerative condition, are characterized by chronic inflammation in brain tissue. Unresolved inflammatory signaling is disruptive of tissue structure and function. Here, researchers provide evidence for T cells to become involved in this...
Source: Fight Aging! - March 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
SARS-CoV-2 infection in adult liver transplantation recipients: a systematic review of risk factors for mortality and immunosuppression role
CONCLUSIONS: Liver transplant patients present additional risk factors of mortality related to immunosuppression. Immunosuppression role in the progression to severe infection and mortality may correlate with different drugs. Moreover, fully vaccinated patients have a lower risk of developing severe COVID-19. The present research suggests safely using TAC and reducing MMF use during the COVID-19 pandemic.PMID:36876704 | DOI:10.26355/eurrev_202302_31413
Source: Pharmacological Reviews - March 6, 2023 Category: Drugs & Pharmacology Authors: F Giovinazzo A Vaccaro M M Pascale F Cardella F Frongillo F Galiandro G Sganga S Agnes Source Type: research
